What Is PGT (Genetic Testing)?

PGT (preimplantation genetic testing/diagnosis) is the genetic examination of embryos before they are transferred to the uterus. A few cells taken from the embryo at the blastocyst stage are analysed to identify chromosomally healthy embryos.

PGT-A screens for chromosome number abnormalities (aneuploidy); it is recommended in advanced maternal age, recurrent miscarriage and recurrent IVF failure. PGT-M, on the other hand, allows a healthy embryo to be selected where a single-gene disease is known in the family (such as SMA, thalassaemia or cystic fibrosis).

Transferring a healthy embryo increases the pregnancy rate, reduces the risk of miscarriage and raises the chance of a healthy birth. At Clavis IVF Center, PGT is carried out safely by our experienced embryology team with blastocyst biopsy. You can see our PGT treatment page for details.

Key Points

• Chromosome analysis before transfer
• PGT-A: numerical abnormalities; PGT-M: single-gene diseases
• Recommended in advanced age and recurrent losses
• Reduces miscarriage risk, improves success